August 18, 2011
Sermorelin Acetate growth hormone releasing hormone therapy is less expensive or about 70% of the cost of genetically engineered recombinant human growth hormone therapy because of the high cost of genetically engineered medication.
- It is medically preferable and safer for the human body to increase the level of human growth hormone and IGF-1 naturally within its own capacity by the use of Sermorelin growth hormone releasing hormone, rather than though the injection of exogenous genetically engineered human growth hormone. This is because the body’s endocrine system safely regulates the amount of additional human growth hormone secreted by the pituitary gland as a consequence of exogenous injections of Sermorelin growth hormone releasing hormone stimulating pituitary production of additional human growth hormone. In contrast, there is no limitation or regulation of the volume of genetically engineered human growth hormone that may be injected by a patient into the body with the resulting potential adverse consequences of high and excessive levels of human growth hormone. Risks include the unsafe and excessive growth or internal organs. Medical research has not found that the body’s endocrine system provides a certain or safe regulation for exogenous source of injected human growth hormone not produced naturally by the body’s pituitary gland. Moreover, possible adverse effects of the use of injected genetically engineered human growth hormone are unknown.
August 5, 2011
What causes testosterone deficiency?
Testosterone is a hormone produced by the testicles and is responsible for the proper development of male sexual characteristics, and is important for maintaining muscle bulk, adequate levels of red blood cells, bone density, sense of well-being, and sexual and reproductive function.
Inadequate testosterone production is not a common cause of erectile dysfunction (ED). When ED does occur with decreased testosterone production, testosterone replacement therapy may improve the ED.
As a man ages, the amount of testosterone in his body gradually declines. This natural decline starts after age 30 and continues throughout life. The significance of this decline is controversial and poorly understood.
Symptoms of testosterone deficiency:
- decreased sex drive
- decreased sense of well-being
- depressed mood
- difficulties with concentration and memory
- erectile dysfunction
What are the changes that occur in the body with testosterone deficiency?
Changes that occur with testosterone deficiency include:
- a decrease in muscle mass, with an increase in body fat
- variable effects on cholesterol metabolism
- a decrease in hemoglobin and possibly mild anemia
- fragile bones (osteoporosis)
- a decrease in body hair
How do I find out if I have a testosterone deficiency?
The only accurate way to detect the condition is to have your doctor measure the amount of testosterone in your blood. It sometimes may take several measurements of testosterone to be sure if a patient has a deficiency, since levels of testosterone tend to fluctuate throughout the day. The highest levels of testosterone are generally in the morning. This is why doctors prefer, if possible, to obtain early morning levels of testosterone.
What options are available for testosterone replacement?
The options available for testosterone replacement are:
- intramuscular injections, generally every two or three weeks
- testosterone patches worn either on the body or on the scrotum (the sac that contains the testicles). These patches are used daily. The body patch application is rotated between the buttocks, arms, back or abdomen.
- testosterone gels that are applied daily to the shoulders, upper arms, or abdomen.
For a free consultation on what would work best for you, contact us at:
email@example.com or call us at 866-641-CORE (2673)
Tags: Anti Aging
, anti aging clinics
, DHEA restoration therapy
, hormone replacement therapy
, HRT CLINICS of Florida
, Low T
, Low Testosterone
, Male Hormone Replacement Therapy Clinic
, male impotence
, Testosterone therapy
Men can benefit from hormone replacement therapy as part of a comprehensive and natural anti-aging program.
As men age, the male hormones decline, referred to as “andropause”. Symptoms of andropause include decrease in muscle mass and muscle strength, increased body fat and lowered libido, accompanied by decrease in mental sharpness and decrease of overall energy levels.
Replacing men’s testosterone as it declines can protect men from a variety of age-related conditions, including:
- Preventing the decline of sexual ability or re-invigorating sexuality if it has already begun to diminish.
- Preventing atherosclerosis, heart attacks, and high blood pressure.
- Minimizing loss of muscle mass and strength common to aging.
- Keeping the prostate gland healthy.
- Prevention of osteoporosisa common problem for men in their 70s.
- Normalizing blood sugar, cholesterol, and HDL (“good”) cholesterol.
Vitamin D benefits are experienced to the fullest extent by people who maintain optimum vitamin D body stores and blood levels.
They can expect better health across the board – longer life (reduction in death from all causes), fewer diseases, stronger bones and muscles, fewer infections, less depression, pain and inflammation. In short, more enjoyment of life.
New vitamin D benefits are still being discovered, almost everywhere researchers look. Here are some of the more important ones discovered so far:
Vitamin D regulates calcium and phosphorus
The first intimation of vitamin D’s vital role was in 1782, when it was discovered that cod liver oil cures rickets (a disease of growing children whose bones bend due to lack of strength). Of course, they didn’t know then that it was vitamin D in the oil that did the job.
Vitamin D itself was isolated in the 1920’s, but for several decades, all that was known about its usefulness was that it prevented rickets.
In fact, vitamin D plays a major role in the absorption of calcium and phosphorus, and in their proper utilization. This helps keep our bones and teeth strong, and stops calcium depositing where it shouldn’t (for example in our blood vessels, heart and kidneys).
Vitamin D is essential to a healthy immune system
Vitamin D helps the immune system to fight infections. With a near-optimum blood level of vitamin D, you can expect fewer colds, ‘flu, and other unwelcome opportunists (including Swineflu).
Not only does Vitamin D enhance your immunity, but it inhibits the development of destructive auto-immune diseases such as diabetes, rheumatoid arthritis, lupus and multiple sclerosis.
Vitamin D is a major inhibitor of cancer, and part of this effect may be attributed to the increased vigilance of the immune system.
Vitamin D promotes cellular differentiation
Vitamin D encourages cell differentiation (differentiated cells are needed to perform specialized functions effectively) and also slows down the rate at which cells multiply, or proliferate.
Both of these effects contribute to vitamin D’s cancer-fighting ability. Cancer cells are characterized by a lack of differentiation and by rapid proliferation.
Vitamin D is a potent anti-inflammatory
Chronic inflammation is coming into prominent focus as a cause of many disease processes, including major killers such as heart disease and cancer.
Vitamin D is a powerful anti-inflammatory agent, which may also contribute to its effectiveness in reducing some types of muscular pain.
Vitamin D helps regulate blood sugar levels
Optimum levels of vitamin D protect against diabetes (both type 1 and type 2), insulin resistance and hyperglycemia. Diabetes is usually associated with very low levels of vitamin D.
The pancreas also needs sufficient vitamin D in order to make and secrete insulin.
Getting enough vitamin D helps blood sugar control. It may also help prevent serious diabetic complications.
Vitamin D helps lower blood pressure
Maintaining adequate levels of vitamin D helps reduce the risk of hypertension. And optimum levels actually tend to reduce blood pressure in hypertensive people.
Vitamin D protects against low-level nuclear radiation
Dr Daniel Hayes PhD describes many ways in which vitamin D may protect the body from the effects of low-level radiation, such as may occur after a nuclear accident. His paper was published in the International Journal of Low Radiation (Sept 2008)
It makes sense that a nutrient that requires you to expose yourself to strong sunlight would help protect against electromagnetic radiation, doesn’t it?.
With the disaster at Fukushima looming large in everyone’s mind, this is a very useful vitamin D benefit.
Vitamin D benefits, or helps prevent, diseases
Scientists are continually reporting that low blood levels of vitamin D are associated with one disease after another. (High vitamin D levels may be protective.)
These diseases have all been linked to low vitamin D levels:
Bones weak (easy to fracture)
Cancer (all types)
Colds and ‘flu
Chronic obstructive pulmonary disease
Dental cavities and misaligned teeth
Diabetes (types 1 and 2)
Low back pain
Mental illness and mood disorders
Muscle weakness and pain
Osteomalacia (softening of bones)
Peripheral artery disease
Pelvic floor disorders
Seasonal affective disorder (SAD)
June 2, 2011
There are a significant number of men and postmenopausal women who can benefit from Testosterone Replacement Therapy. Although it is only replaced in men, women can benefit from a renewed partner.
The andropausal symptoms can be helped and even reversed by the right supplementation of testosterone into the body. The idea of testosterone therapy is to restore testosterone to youthful levels to achieve optimal health and well-being. Testosterone is a vital hormone that plays an enormous role in the sex drive of both men and women. It is known to restore healthy sexual excitement and desire, which in turn improves attitude, relationships and well-being.
The key to anti-aging is linked to simply replacing hormone levels to what they once were in our youthful days.
Male menopause is referred to as Andropause, and is very common in the average aging male. Most people are under the impression that there is no menopause for men, just women. Symptoms for the male are kept quiet and are said to just be a part of old age. Male menopause does exist and only rarely do men get “”hot flashes,”” but there is an increase in morning and nightly fatigue and the male’s erections are less often, less firm, and ejaculation takes place less often. Many men who have used Testosterone Replacement Therapy reach a maximum improvement of sexual function within 30 days. Body fat was decreased in many studies, lean muscle strength increased, and better cardiac health overall was reported.
April 6, 2011
The Purpose of Sermorelin Acetate Therapy
The purpose of Sermorelin Acetate Therapy is to cause the pituitary gland to increase growth hormone production in humans. The purpose of adult Sermorelin growth hormone therapy is to reverse the effects of aging and secure the extensive treatment benefits described below.
What is Sermorelin Acetate GH-RH?
Sermorelin Acetate is a “growth hormone-releasing hormone” (GHRH). This prescription drug is compounded by U.S. pharmacies pursuant to a physician’s prescription and is patient self-injected subcutaneously. It stimulates the pituitary gland to naturally produce increased amounts of human growth hormone. Sermorelin Acetate is a truncated analog of a growth hormone releasing factor (GRF 1-44) that is naturally produced by the brain to stimulate pituitary production of human growth hormone. The increased volume of human growth hormone (hGH) produced by the pituitary gland causes an increase in the production of Insulin-Like Growth Factor-1 (IGF-1) by the liver and results in the benefits of treatment provided to the adult patient.
Benefits of Sermorelin Acetate Growth Hormone Releasing Hormone Therapy
- Increases the development of lean body mass through the development of new muscle cells
- Reduces body fat through lipolysis
- Increases energy and vitality
- Increases strength
- Increases endurance
- Accelerates healing from wounds or surgery
- Strengthens the heart
- Enhances the immune system
- Increases IGF-1 production
- Improves sleep quality
- Increases calcium retention, and strengthens and increases the mineralization of bone or bone density.
- Increases protein synthesis and stimulates the growth of all internal organs except the brain.
- Plays a role in fuel homeostasis.
- Eeduces liver uptake of glucose, an effect that opposes that of insulin.
- Promotes liver glucogenesis.
- Contributes to the maintenance and function of pancreatic islets.
Sermorelin Growth Hormone (GHRH) Therapy
As a result of Sermorelin Growth Hormone (GHRH) Therapy, the increased volume of human growth hormone secreted by the stimulated pituitary gland is converted by the liver into IGF-1. The increased amount of IGF-1 in the blood stream results an increase in metabolism and growth of new cells within the body’s organs and bones. This treatment is prescribed for unlabeled use in adults to reverse the effects of aging, increase bone density, enhance the immune system, and strengthen the heart, as well as, other organs of the body. Since the increased volume of human growth hormone is produced by the body’s pituitary gland, the body’s endocrine system will not allow more growth hormone to be produced by the Sermorelin GH-RH stimulation of the pituitary than the body can safely process within the endocrine self-monitoring system.
Growth Hormone – Releasing Hormone (Sermorelin Acetate) has been specifically approved for medical use in increasing growth hormone levels in children deficient in growth hormone production. Its use to increase the growth hormone and IGF-1 levels in adults is an off-label use of this prescription drug and not the approved use. It is specifically approved only for use in children and was formerly manufactured under the prescription drug brand name of Geref.
Growth Hormone – Releasing Hormone (Sermorelin Acetate) Therapy causes the pituitary gland to increase the growth hormone and IGF-1 levels in humans. It is a prescription drug that may be prescribed for adults for unlabeled uses and the cost is about one-third the price of illegal adult synthetic, recombinant human growth hormone (HGH) injections therapy.
Growth Hormone – Releasing Hormone (Sermorelin Acetate) Therapy for Adults increases adult lean muscle mass, reduces body fat and reverses the effects of aging in adults because of the benefits flowing from its stimulation of the pituitary gland to increase production of human growth hormone and the resulting increased production of IGF-1by the liver.
Prescribing of Recombinant Human Growth Hormone (HGH) (somatropin) for Adults without Pituitary Disease is Illegal Under Federal Law, but Sermorelin Acetate GH-RH May Legally be Prescribed
As you may be aware, it is now against federal law and a felony to prescribe, possess or distribute recombinant human growth hormone (HGH) (a synthetic, genetically engineered, growth hormone (somatropin) to an adult, unless they have been diagnosed as having a pituitary disease or suffer from AIDS muscle wasting. The relevant federal statute and the assignment of jurisdiction for enforcement of this law to the U.S. Drug Enforcement Agency may be found by clicking on the link entitled “Warning to Online Buyers About Sites Offering Illegal Prescriptions” located on our website home page http://www.nationalmedicalclinic.com/ or by clicking on the following link: http://www.nationalmedicalclinic.com/comp_warning.php Many clinic owners, pharmacists and physicians have been indicted and convicted of felony distribution or possession (pharmacist dispensing or physician prescribing) of HGH for the unapproved purposes of medical rejuvenation, accelerated wound healing or anti-aging in recent years. The injection of recombinant HCG can result in the variations if growth of internal organs because the drug is not regulated by the body’s endocrine system as is Sermorelin GH-RH. However, no law prohibits the prescribing of Growth Hormone – Releasing Hormone (Sermorelin Acetate) to adults for such unlabeled purposes. Further, the possession of recombinant growth hormone illegally or invalidly prescribed by a physician results in criminal possession of the drug by the patient
Sermorelin Growth Hormone (GH-RH) Therapy offers several advantages over genetically engineered synthetic human growth hormone (HGH):
As you may be aware, it is now against federal law and a felony to prescribe, possess or distribute recombinant human growth hormone (HGH) (a synthetic, genetically engineered, growth hormone (somatropin) to an adult, unless they have been diagnosed as having a pituitary disease or suffer from AIDS muscle wasting. The relevant federal statute and the assignment of jurisdiction for enforcement of this law to the U.S. Drug Enforcement Agency may be found by clicking on the link entitled “Warning to Online Buyers About Sites Offering Illegal Prescriptions” located on our website home page http://www.nationalmedicalclinic.com/ or by clicking on the following link: http://www.nationalmedicalclinic.com/comp_warning.php Many clinic owners, pharmacists and physicians have been indicted and convicted of felony distribution or possession (pharmacist dispensing or physician prescribing) of HGH for the unapproved purposes of medical rejuvenation, accelerated wound hearing or anti-aging in recent years. The injection of recombinant HCG can result in the variations if growth of internal organs because the drug is not regulated by the body’s endocrine system as is Sermorelin GH-RH. However, no law prohibits the prescribing of Growth Hormone – Releasing Hormone (Sermorelin Acetate) to adults for such unlabeled purposes. Further, the possession of recombinant growth hormone illegally or invalidly prescribed by a physician results in criminal possession of the drug by the patient
Sermorelin Growth Hormone (GH-RH) Therapy offers several advantages over genetically engineered synthetic human growth hormone (HGH):
- Sermorelin GH-RH may legally be prescribed for unlabeled use in adults deficient in human growth hormone, while synthetic, genetically engineered (recombinant) HGH (somatropin) may not legally be prescribed for adults, except (1) to treat adult HIV muscle wasting, or (2) a growth hormone deficiency resulting from a physician diagnosed pituitary disease based upon objective diagnostic medical laboratory testing. It is a felony and federal crime for a U.S. physician, pharmacist, pharmacy, clinic, organization or person to knowingly possess or distribute synthetic, genetically engineered (recombinant) human growth hormone (somatropin or HGH) to any adult patient for the purpose of medical rejuvenation, reversing the effects of aging, accelerate recovery from surgery or injuries, strengthen the heart, or any other purpose not expressly approved by the Secretary of Health and Human Services. The applicable federal criminal statute is US Code Annotated, Title 21 Food and Drugs, Chapter 3, Subchapter III, Section 333. (e) (1).
- Sermorelin Growth Hormone (GH-RH) Therapy cost about 1/3 of the prices charged by physicians, pharmacies, clinics and others for the knowingly possessing, prescribing, distributing or dispensing of synthetic, genetically engineered human growth hormone HGH (somatropin) for unapproved and illegal medical uses ; and,
- Sermorelin Growth Hormone (GH-RH) injected into the body are safer than HGH injections because the increased human growth hormone is produced by the body’s pituitary gland; and the endocrine system will not allow the pituitary to produce more human growth hormone than the body can safely process. Therefore, the body’s organs cannot grow at different rates as they do with illegal, synthetic, recombinant, genetically engineered human growth hormone (HGH) or somatropin. Hence, a potential serious adverse side effect of excessive dosing is avoided with the use of Sermorelin Acetate.
TESTOSTERONE AND HCG THERAPY – FUNCTIONS AND BENEFITS
Function of Testosterone
Testosterone is the most important sex hormone or androgen produced in men. The function of testosterone is primarily the producing the normal adult male characteristics. During puberty, testosterone stimulates the physical changes that constitute the attributes of the adult male.
Throughout adult life, testosterone helps maintain sex drive, the production of sperm cells, male hair patterns, muscle mass and bone mass. Testosterone is produced in men by the testes and in the outer layer of the adrenal glands.
The hypothalamus controls hormone production in the pituitary gland by means of gonadotropin-releasing hormone (GnRH). This hormone tells the pituitary gland to make follicle-stimulating hormone (FSH) and Luteinizing hormone (LH). LH orders the testes to produce testosterone. If the testes begin producing too much testosterone, the brain sends signals to the pituitary to make less LH. This, in turn, slows the production of testosterone. If the testes begin producing too little testosterone, the brain sends signals to the pituitary gland telling it to make more LH, which causes the testes to make more testosterone.
Symptoms of Low Testosterone
The failure of the testes to produce a sufficient level of testosterone in the adult male results in a low testosterone level. Physical signs of low testosterone in men may include:
- Declining sex drive,
- Erectile dysfunction (ED)
- Low sperm count
- Decrease in lean muscle mass
- Insomnia or sleep disorder
- Chronic fatigue.
Conditions Causing Male Testosterone Deficiency
Testosterone deficiency can be caused by different conditions: 1) effects of aging; 2) testes based conditions; 3) genetics; and 4) conditions caused by the pituitary and hypothalamus.
- The effects of aging on testosterone production
- Testes disorder
- Pituitary/Hypothalamus disorder
- Genetically-based condition
Function of Testosterone Therapy
The function of testosterone hormone replacement therapy is to increase the level of testosterone in the adult male diagnosed with testosterone deficiency (low testosterone) or hypogonadism. Testosterone replacement should in theory approximate the natural, endogenous production of the hormone. The clinical reasons for treatment of testosterone deficiency in men include:
- Increased male sex drive
- Improve male sexual performance
- Enhance mood in men
- Reduce depression in men
- Increased energy and vitality
- Increase bone density
- Increased strength and endurance
- Reduce body fat
- Increase body hair growth
- Reduce risk of heart disease
- Develop lean muscle mass with exercise
Function of HCG Therapy is to Stimulate the Testes to Prevent Loss of Natural Testosterone Production and Avoid Testicular Atrophy while the Male Patient is Undergoing Testosterone Hormone Replacement Therapy
The hormone HCG is prescribed for men in this therapy to increase natural testosterone production during the course of therapy as a result of the stimulation of the testes by the HCG. No testosterone medication is administered in this treatment. The treatment objective is to cause the male testes to naturally produce a higher volume of testosterone by HCG stimulation of his testes with the result that the patient experiences a continuing higher blood level of testosterone while on treatment. Another treatment objective is to avoid the use of any anabolic steroid and its adverse side effects upon the patient.
HCG Therapy normally increases natural testosterone production by the male testes while HCG is administered to the patient during the treatment period However, HCG Therapy can also result in a continuation of increased testosterone production and a resulting higher level of testosterone in the bloodstream after treatment is completed when the cause of the patient’s low natural LH secretion by the pituitary is not due to the patient’s natural genetics, aging process, injury to or loss of one or both testes; a medical disorder or disease affecting the testes, or castration.
HCG Therapy can result in a continuing higher level of natural testosterone production by the testes after HCG Therapy is completed when the underlying cause of the low LH secretion and resulting low testosterone production (1) is due to the prior use of one or more anabolic steroids by the patient or (2) due to the administration of testosterone in a prior hormone replacement therapy without the required concurrent HCG Therapy to prevent the patient’s endocrine system (hypothalamus pituitary-testes axis) from shutting down the natural production of testosterone by the testes and causing testicular atrophy.
Types of Testosterone Therapy for Men
A good male testosterone replacement therapy produces and maintains physiologic serum concentrations of testosterone and its active metabolites without significant adverse side effects.
The leading types of testosterone therapy for men include:
- Testosterone Injection with HCG
- Testosterone Transdermal Cream with HCG
- Testosterone Transdermal Gel with HCG
Benefits of HCG Therapy for the Male Patient Undergoing Testosterone Hormone Replacement Therapy
- Increases natural testosterone production by the testes
- Prevents loss of natural testosterone production by the testes while the male patient is undergoing testosterone hormone replacement therapy
- Prevents atrophy of testes while male patient is being treated with testosterone replacement therapy
- Increases physical energy and elimination of chronic fatigue
- Improves sex drive
- Improves sexual performance
- Improves mood
- Reduces depression
- Increases lean muscle mass
- Increases strength and endurance as a result of exercise
- Reduces body fat due to increased exercise
- Increases sperm count and therefore male fertility
- HCG Therapy can also result in a higher level of natural testosterone production after HCG Therapy is completed when the cause of a man’s current low testosterone production is the prior use of anabolic steroids that shut down or reduced the pituitary gland’s production of LH and decreased testosterone production.
Human Chorionic Gonadotropin (HCG)
HCG is compounded by a compounding pharmacy or manufactured by pharmaceutical company in 10,000 IU (International Units) for reconstitution with sterile water for injections in 10 cc vials.
HCG is a natural protein hormone secreted by the human placenta and purified from the urine of pregnant women. HCG hormone is not a natural male hormone but mimics the natural hormone LH (Luteinizing Hormone) almost identically. As a result of HCG stimulating the testes in the same manner as LH, HCG therapy increases testosterone production by the testes or male gonads as a result of HCG’s stimulating effect on the leydig cells of the testes.
The Decline in Gonadal Stimulating Pituitary Hormone LH (Leutenizing hormone)
The natural decline in male testosterone production that occurs with aging is attributed to a decline in the gonadal stimulating pituitary hormone LH (Luteinizing hormone). As a result of the hypothalamus secreting less gonadoropin-releasing hormone (GhRH), which stimulates the pituitary gland to produce LH, the pituitary gland produces declining amounts of LH. This decrease in the pituitary secretion of LH reduces the stimulation of the gonads or male testes and results in declining testosterone and sperm production due to the decreased function of the gonads. The decreased stimulation of the testes by the pituitary’s diminished secretion of LH can also cause testicular atrophy. HCG stimulates the testis in the same manner as naturally produced. HCG Therapy is administered medically to increase male fertility by stimulating the testes to produce more sperm cells and thereby increase sperm count or Spermatogenesis.
The decreased stimulation of the testes by the pituitary’s diminished secretion of LH can also cause testicular atrophy. HCG stimulates the testis in the same manner as naturally produced. HCG Therapy is administered medically to increase male fertility by stimulating the testes to produce more sperm cells and thereby increase sperm count or Spermatogenesis.
How HCG Therapy Increases Plasma Testosterone Level in Men with Low Testosterone Production
HCG therapy uses the body’s own biochemical stimulating mechanisms to increase plasma testosterone level during HCG therapy. It is used to stimulate the testes of men who are hypogonadal or lack sufficient testosterone. The male endocrine system is responsible for causing the testes to produce testosterone. The HPTA (hypothalamic-pituitary-testicular axis) regulates the level of testosterone in the bloodstream. and . The hypothalamus produces gonadotropin-releasing hormone (GnRH), which stimulates the pituitary gland to release Leutenizing hormone (LH).
LH released by the pituitary gland then travels from the pituitary via the blood stream to the testes where it triggers the production and release of testosterone. Without the continuing release of LH by the pituitary gland, the testes would shut down their production of testosterone, causing testicular atrophy and stopping natural testosterone produced by the testes.
As men age the volume of hypothalamus produced gonadotropin-releasing hormone (GnRH) declines and causes the pituitary gland to release less Luteinizing hormone (LH). The reduction if the volume of LH released by the Pituitary gland decreases the available LH in the blood stream to stimulate the testes to produce testosterone.
In males, HCG mimics LH and increases testosterone production in the testes. As such, HCG is administered to patients to increase endogenous (natural) testosterone production. The HCG medication administered combines with the patient’s own naturally available LH released into the blood stream by the Pituitary gland and thereby increases the stimulation of the testes to produce more testosterone than that produced by the Pituitary released LH alone. The additional HCG added to the blood stream combined with the Pituitary gland’s naturally produced LH triggers a greater volume of testosterone production by the testes, since HCG mimics LH and adds to the total stimulation of the testes.
HCG Clinical Pharmacology
The action of HCG is virtually identical to that of pituitary LH, although HCG appears to have a small degree of FSH activity as well. It stimulates production of gonadal steroid hormones by stimulating the interstitial cells (Leydig cells) of the testis to produce androgens.
Thus HCG sends the same message and results in increased testosterone production by the testis due to HCG’s effect on the leydig cells of the testis. HCG therapy uses the body’s own biochemical stimulating mechanisms to increase plasma testosterone level.
Following intramuscular injection, an increase in serum HCG concentrations may be observed within 2 hours; peak HCG concentrations occur within about 6 hours and persist for about 36 hours. Serum HCG concentrations begin to decline at 48 hours and approach baseline (undetectable) levels after about 72 hours.
HCG is not a steroid and is administered to assists the body in the continuing production of its own natural testosterone as a result of LH signals stimulating production of testosterone by the testis.
This LH stimulates the production of testosterone by the testes in males. Thus HCG sends the same message as LH to the testes and results in increased testosterone production by the testes due to HCG’s effect on the leydig cells of the testes. In males, hCG mimics LH and helps restore and maintain testosterone production in the testes. If HCG is used for too long and in too high a dose, the resulting rise in natural testosterone will eventually inhibit its own production via negative feedback on the hypothalamus and pituitary.
HCG therapy uses the body’s own biochemical stimulating mechanisms to increase plasma testosterone level during HCG therapy. It is used to stimulate the testes of men who are hypogonadal or lack sufficient testosterone
January 3, 2011
Crohn’s disease is a chronic disorder of the gastro intestinal tract, which is characterized by inflammation, and causes difficult digestion and general disability. Crohn’s is one of the very common irritable bowel syndromes / diseases (IBS/D) which affects several hundreds of individuals. In addition to Crohn’s disease, ulcerative colitis is another IBD which is common.
There have been some research studies in the recent past, which have indicated the potential benefits of the Human Growth Hormone Replacement Therapy, to treat patients with Crohn’s disease. A dietary modification which comprises of high protein diet and an adequate intake of folvite has been suggested, in addition to the hormone replacement therapy to effectively manage the condition.
Research indicating the role of the Human Growth Hormone in the management of Crohn’s Disease
A study was conducted on thirty seven adults suffering from moderate to severe form of active Crohn’s disease, by Dr. Alfred Slonim and his colleagues at the North Shore University Hospital in Manhasset, New York. The participants were administered 5 mg of HGH with a maintenance dose of 1.5 mg for a period of four months. Also, dietary modifications were suggested to the case and the control groups.
For a period of four months, the disease activity was evaluated using Crohn’s Disease Activity Index. It was observed that in patients treated with HGH, the improvement was about 100 %. Minor side effects were observed in the case group (i.e. participants treated with HGH) which included: edema and headache, which disappeared after the first month of the treatment. The study concluded that HGH has significant benefits in the management of patients suffering from Crohn’s Disease and it also aids in making the intestinal tissue healthier. The study was published in the New England Journal of Medicine in 2000. The study also observed that the benefit of Growth hormone was similar to the use of anti inflammatory drug infliximab (which is the only approved treatment for patients with Crohn’s disease).
HGH treats Crohn’s disease effectively
Crohn’s Disease is manifested in the form of abdominal pain, diarrhea and bleeding, due to a breakdown of the intestinal wall. Unfortunately, neither the cause nor an approved treatment solution for the same is available. One of the reasons cited for the development of the condition is an exaggerated immune response which results in tissue damage.
There is little information about how HGH assists in the management of Crohn’s disease; nevertheless, a rational explanation is available. HGH improves cell mediated response to antibodies and programs the immune system to respond by creating specific antigens. This is one of the reasons why HGH has been potentially beneficial in patients suffering from HIV/AIDS or from autoimmune disorders like lupus and arthritis. Secondly, HGH promotes organ restoration and helps in the growth and proliferation of intestinal tissue, which in turn, improves the patient’s clinical condition.
The Human Growth Hormone is a potential solution for patients suffering from IBS including Crohn’s disease, especially, in conjunction with dietary and life style changes.
The human growth hormone is produced by the pituitary gland. This hormone induces the secretion of insulin like growth factor-1 which has the capacity to heal injured cells and generate new ones. It can also increase bone mineral density, make the joints and ligaments strong and sustain good muscle tone.
Clinical studies and research discloses that HGH has an important role to play in promoting general health and wellness. It strengthens muscles, tendons and ligaments, accelerates wound healing, encourages rejuvenation and builds lean muscle. Proper diet, sleep and exercise are good inducers and triggers of the hormone.
With age, ligaments and tendons wear out. Demineralization of bones occurs, reducing bone density. Wear and tear of the cartilage takes place. The cartilage may also lose water (synovial fluid) and eventually become rigid. This makes the joint painful due to gradual damage to the cartilage. It reduces joint flexibility, diminishes the range of movement and causes pain and discomfort. Arthritis invariably afflicts the hip and knee joints. The condition can be treated using non-steroidal anti-inflammatory drugs. However, these drugs offer only temporary relief. They alleviate pain, but can not repair the underlying problem. Pain killers bring only momentary relief, but fail to regenerate the cartilage tissue which is essential for a flexible and supple joint.
The best treatment option for this problem is intra-articular administration of the human growth hormone. HGH is administered into the joint every 1 or 2 weeks. This allows the cells of the bone to change into cartilage cells. This process is defined as “Morphoangiogenesis”. This process was further studied by an orthopedic surgeon, Allan Dunn at Florida. He suggested that the growth hormone treatment must be performed when no other treatment is going on, as it could damage the growth hormone integrity and in turn the functionality.
HGH therapy improves joint movement and flexibility. It decreases pain, discomfort, and stiffness, while strengthening all the components of the locomotor system.
There is adequate experimental and clinical evidence that suggests that the use of the Human Growth Hormone can improve diabetes. In a study conducted at John Hopkins Institute, it was observed that HGH regulated glucose levels in the blood, while, concurrently reducing intra-abdominal fat. As per Dr. Hertoghe, of Brussels, HGH enhances the action of insulin and enhances the absorption of glucose by the nerve cells, cardiac cells and muscular cells. This prevents the absorption of glucose by fat cells which has a beneficial action on insulin sensitivity and controlling diabetes. Furthermore, lower levels of blood sugar reduce other harmful complications of diabetes including, diabetic retinopathy, cardiac illness and peripheral nerve disease.
Research to substantiate the role of HGH in improving diabetes
In a study conducted by Johannson and his colleagues, at the Salgrenska University Hospital, it was found that HGH helps improve insulin sensitivity. The study design was a randomized double blind study involving 30 men between the age groups of 48 years to 66 years. These individuals were given low doses of HGH for a period of nine months, and great benefits of the same were observed. Glucose metabolism improved considerably, along with an average reduction of 18.1 % of abdominal fat, which has been considered to be a major cause of insulin resistance. The study concluded that HGH replacement therapy helps improve insulin sensitivity and assists in regulation of blood sugar levels.
In another double blind study conducted in 1997, it was observed that IGF-1 (an intermediate factor secreted by the liver on stimulation by HGH) can reduce the need for insulin by up to 45 %, in patients suffering with insulin dependent diabetes mellitus. The study involved eight adults, between the age group of 24 to 49 years, and forty three children between the ages of 8 to 17 years.
IGF-1 was also found to lower the levels of cholesterol and triglycerides in the blood after a mere four days of treatment. The study was a short clinical trail lasting for four weeks. No serious side effects of HGH replacement therapy were observed in any of the participants.
As per Dr. Fahy at the Naval Medical Research Institute, experiments have shown that HGH is beneficial in controlling diabetes and can be considered as a possible cure for adult onset diabetes.
How does HGH help improve diabetes?
Most of the potential benefits of HGH replacement therapy, for the management of diabetes, arises from the production of IGF-1 (a factor which is released by the liver on stimulation by HGH). IGF-1 is insulin like growth factor which has action similar to insulin and enhances the absorption of glucose from the blood by cells in the body.
Under normal conditions, glucose is absorbed by the adipose cells / fat cells, after requisite amounts of glucose are absorbed by other body cells (i.e. skeletal muscles, cardiac muscles and nerve tissue). However, with IGF-1 in the blood, the absorption of glucose by body cells in increased in comparison to adipose tissue cells. This has a dual advantage of reducing the fat deposition in the body and concurrently reducing the levels of blood sugar. HGH also has a potent action on improving protein metabolism and enhancing protein synthesis. This in turn regulates glucose metabolism in the body and increases sensitivity of receptors to insulin.
There is overwhelming evidence of the immense benefits of HGH replacement therapy in the management of insulin dependent diabetes. Though, it is recommended that the treatment should be taken in conjunction to dietary measures, the benefits of the treatment are many, including averting the detrimental side effects of diabetes like – diabetic retinopathy, kidney damage and a likelihood of developing cardio vascular disease.